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5-HTP

Physical Product · Supplements & vitamins · 12 mentions · 1 subreddit · discussed in r/Supplements

Reddit take

Not enough linked mention summaries yet; the source excerpts below are the evidence.

Pros

  • In the evening, I use 5-HTP (200 mg) with KSM-66 Ashwagandha (600 mg) and Melatonin (5 mg) and these put me to sleep like …
  • Today the 3rd day of taking it I woke up and feel better than I have in literal years. I have so much energy I wokeup feeling amazing it just feels like natural dopamine. I feel so good I almost feel “high” .
  • I have and it does work! I keep hearing about heart valve complications with 5htp so I decided to switch just to be safe. But never experienced any issues myself when i was on it.
  • Parent context: can you give some informations about 5-htp, i saw this last times so much Reply: It’s amazing but don’t take if your on SSRI and take it at night you’ll sleep amazing. It’s like a natural antidepressant it’s been life cha...
  • I actually got my depression fully under control by quitting nicotine and taking 5-htp & L-tyrosine. This is the first time in life I’ve felt ok.

Cons

  • 5-HTP - Helped initially but after 3 weeks I felt depressed and irritable.
  • Administration of 5-HTP alone depletes catecholamines (dopamine, norepinephrine, and epinephrine).
  • 5htp? 200mg is what I've taken, it never felt right and never took it longer than a week.
  • There's no scientific evidence to back up 5htp claims at all - marketing spin I think.
  • 5-hpt is not something that comes to mind for insomnia. It actually seems somewhat stimulating to me.

Sentiment

7 positive (58%) · 1 mixed (8%) · 4 negative (33%)

Trust + time weighted score: +27% · raw score 25%

What redditors said (10 of 12)

In the evening, I use 5-HTP (200 mg) with KSM-66 Ashwagandha (600 mg) and Melatonin (5 mg) and these put me to sleep like …
positive · u/T****1 · r/Supplements · comment · Dec 24, 2025 · open on Reddit ↗
In the evening, I use 5-HTP (200 mg) with KSM-66 Ashwagandha (600 mg) and Melatonin (5 mg) and these put me to sleep like a baby.
positive · u/T****1 · r/Supplements · comment · Dec 24, 2025 · open on Reddit ↗
5-HTP - Helped initially but after 3 weeks I felt depressed and irritable.
negative · u/M****5 · r/Supplements · Dec 2, 2025 · open on Reddit ↗
Administration of 5-HTP alone depletes catecholamines (dopamine, norepinephrine, and epinephrine).
negative · u/a****l · r/Supplements · comment · Nov 12, 2025 · open on Reddit ↗
Today the 3rd day of taking it I woke up and feel better than I have in literal years. I have so much energy I wokeup feeling amazing it just feels like natural dopamine. I feel so good I almost feel “high” .
positive · u/E****5 · r/Supplements · Nov 12, 2025 · open on Reddit ↗
I have and it does work! I keep hearing about heart valve complications with 5htp so I decided to switch just to be safe. But never experienced any issues myself when i was on it.
positive · u/s****h · r/Supplements · comment · Jul 14, 2025 · open on Reddit ↗
Parent context: can you give some informations about 5-htp, i saw this last times so much Reply: It’s amazing but don’t take if your on SSRI and take it at night you’ll sleep amazing. It’s like a natural antidepressant it’s been life changing for me
positive · u/S****5 · r/Supplements · comment · Feb 17, 2025 · open on Reddit ↗
I actually got my depression fully under control by quitting nicotine and taking 5-htp & L-tyrosine. This is the first time in life I’ve felt ok.
positive · u/S****5 · r/Supplements · comment · Feb 3, 2025 · open on Reddit ↗
5htp? 200mg is what I've taken, it never felt right and never took it longer than a week.
mixed · u/1****O · r/Supplements · comment · Jan 5, 2025 · open on Reddit ↗
works for me 10 times better than just tryptophan
positive · u/V***u · r/Supplements · comment · Jan 5, 2025 · open on Reddit ↗

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