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Spironolactone vs Sulfur Ointment

Spironolactone (133 mentions) vs Sulfur Ointment (5 mentions): verbatim Reddit excerpts, sentiment split and trust-weighted score side by side.

Spironolactone

Acne treatments · 133 mentions · 1 subreddit · #3 of 31 in Acne treatments

89 positive (67%) · 20 mixed (15%) · 24 negative (18%)

Trust + time weighted: +50%

AI summary — not a quote

Spironolactone is widely regarded by Reddit users as a highly effective prescription treatment for hormonal and cystic acne, particularly in adult women. It works by suppressing androgens, making it a common choice for managing acne related to PCOS or hormonal fluctuations. While many describe it as a "life-changer" or "miracle" for skin that failed to respond to other treatments, it is noted for requiring a long-term commitment and several months of consistent use before results become apparent.

Pros

  • Highly effective for hormonal and cystic acne that resists topical treatments
  • Addresses the root cause of acne by blocking androgens
  • Can clear persistent body and back acne
  • Often successful for managing skin symptoms associated with PCOS

Cons

  • Slow onset of action, often requiring 3 to 5 months to see significant improvement
  • Acne frequently returns once the medication is discontinued
  • Potential for significant side effects that some users find difficult to tolerate
  • Lower doses (e.g., 25mg) may be ineffective for some individuals

Top excerpts

If you have excess androgens, then Spironolactone is prescribed to bring your levels down to normal. Spearmint acts on a similar pathway and dramatically drops testosterone. This is great for PCOS.
positive · u/-****- · r/SkincareAddiction · comment · Feb 20, 2026 · open on Reddit ↗
I know the prescription spironolactone works for cystic acne because it suppresses androgens.
positive · u/O****1 · r/SkincareAddiction · comment · Feb 20, 2026 · open on Reddit ↗
spironolactone works wonders for my adult acne
positive · u/r****y · r/SkincareAddiction · comment · Mar 4, 2026 · open on Reddit ↗
I’m so glad I started birth control and spironolactone it was the magic combo to control my acne and I’ve been on them for 15 years.
positive · u/r****y · r/SkincareAddiction · comment · Jan 25, 2026 · open on Reddit ↗
Birth control and spironolactone did wonders for my skin, I had no side affects thankfully
positive · u/r****y · r/SkincareAddiction · comment · Jan 25, 2026 · open on Reddit ↗

Sulfur Ointment

Acne treatments · 5 mentions · 1 subreddit · #5 of 31 in Acne treatments

5 positive (100%) · 0 mixed (0%) · 0 negative (0%)

Trust + time weighted: +100%

Top excerpts

I’d go for sulfur ointment over anything, if you have a choice
positive · u/H****z · r/SkincareAddiction · comment · Mar 1, 2026 · open on Reddit ↗
Warm compress is a great suggestion, also sulfur ointment has saved me from some gnarly ones! I apply the De La Cruz stuff and leave on for at least half an hour.
positive · u/S****x · r/SkincareAddiction · comment · Mar 19, 2026 · open on Reddit ↗
sulfur ointment has been a game changer for blemishes and even ingrown hairs for me. I bet combining it with steam would make it even better, softening sebum/plugs and relaxing pores per se to help the sulfur do its thing. I'm a big believer in sulfur.
positive · u/S****x · r/SkincareAddiction · comment · Mar 19, 2026 · open on Reddit ↗
Sulfur ointment is lovely, maybe do some barrier repair first to be safe; I like to layer snail mucin under Cicaplast b+, but zinc ointment is great as well. The sulfur is very gentle and works wonders for blemishes.
positive · u/S****x · r/SkincareAddiction · comment · Feb 15, 2026 · open on Reddit ↗
if it doesn’t work, see about regular sulfur ointment that’s in a cream form you can apply to your skin directly?
positive · u/c****e · r/SkincareAddiction · comment · Mar 19, 2026 · open on Reddit ↗