Side by side
Spironolactone vs Mupirocin
Spironolactone
89 positive (67%) · 20 mixed (15%) · 24 negative (18%)
Trust + time weighted: +50%
AI summary — not a quote
Spironolactone is widely regarded by Reddit users as a highly effective prescription treatment for hormonal and cystic acne, particularly in adult women. It works by suppressing androgens, making it a common choice for managing acne related to PCOS or hormonal fluctuations. While many describe it as a "life-changer" or "miracle" for skin that failed to respond to other treatments, it is noted for requiring a long-term commitment and several months of consistent use before results become apparent.
Pros
- Highly effective for hormonal and cystic acne that resists topical treatments
- Addresses the root cause of acne by blocking androgens
- Can clear persistent body and back acne
- Often successful for managing skin symptoms associated with PCOS
Cons
- Slow onset of action, often requiring 3 to 5 months to see significant improvement
- Acne frequently returns once the medication is discontinued
- Potential for significant side effects that some users find difficult to tolerate
- Lower doses (e.g., 25mg) may be ineffective for some individuals
Top excerpts
If you have excess androgens, then Spironolactone is prescribed to bring your levels down to normal. Spearmint acts on a similar pathway and dramatically drops testosterone. This is great for PCOS.
I know the prescription spironolactone works for cystic acne because it suppresses androgens.
spironolactone works wonders for my adult acne
I’m so glad I started birth control and spironolactone it was the magic combo to control my acne and I’ve been on them for 15 years.
Birth control and spironolactone did wonders for my skin, I had no side affects thankfully
Mupirocin
6 positive (100%) · 0 mixed (0%) · 0 negative (0%)
Trust + time weighted: +100%
Top excerpts
I went to an urgent care and was prescribed Mupirocin ointment. Apply 2x daily with a cotton swab. Went away in 2 weeks.
Mupirocin is also what worked for me, but to be clear it is anti bacterial and not anti fungal. Staph is often involved in these infections, and mupirocin is the most effective treatment for staph.
I tried everything for the angular cheilitis for months and nothing worked except mupirocin which cleared it within days.
Mupirocin works fast. I had it prescribed for some crazy skin infection from a hot tub. By the next day all the painful bits cleared up, and it was just redness and bumps.
I was prescribed mupirocin, and my friend also mentioned colloid bands as a way to prevent scarring. Obviously I also know that once this heals I’ll need to apply sunscreen everyday, and until then I’m keeping nonadherent bandages on it with mupirocin applied.